In recent years there has been an increasing need for transplantation, but the number of donor livers available has increased only slightly, despite intensive public relations activities. New concepts in the field of transplantation, for instance the transplantation of living donor organs or the splitting of organs, are urgently required, to safeguard the treatment of patients with severe liver disease. The development and clinical application of cell therapy for patients with liver disease could soon present a significant enhancement of the therapeutic options. The aim of such cell therapy is to repair or improve the biological function of the chronically and acutely damaged liver. Even though systematic trials are not available, individual case reports and small series already show promising clinical results. Present concepts of cell therapy for liver diseases based on the use of primary hepatocytes have recently been considerably extended through new data on the biology of stem cells. The adult haematopoetic stem cell as a pool for hepatocyte grafts - what would be the perspectives for the clinical application? This book is the proceedings of the Falk Symposium No. 126 on `Hepatocyte Transplantation´ (Progress in Gastroenterology and Hepatology Part III) held in Hannover, Germany, October 2-3, 2001, and is a forum for basic research, but also for questions concerning clinical applications in the field of hepatocyte transplantation.
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. First performed in the early 1960s, a lung transplantation is a surgical procedure designed for people with severe lung conditions, in which one or both damaged lungs are replaced with healthy lungs from a human donor. According to statistics, since the early 1990s, more than 25,000 lung transplantations have been performed worldwide. Taking into account the fact that lung replacement patients have to wait a long period until a new lung transplant becomes available, a new British study found out that patients who received lung transplants from smokers, are more likely to survive than those who refuse such lungs and remain on the transplant waiting list. To find out more about the lung transplantation - read this book.
The book is designed to highlight recent updates in living related transplants, with chapters by leaders in the different types of transplantation. There are very few texts that tackle living donor liver, lung, pancreas and intestinal transplantation as well as the connected ethical issues. With some color photographs illustrating procedures, this concise book will be a valuable resource for students or professionals interested in developing a global view of the ethics and practice of transplantation.
Remarkable developments in the field of transplantation have created opportunities to address the formidable challenges of transplantation across histocompatibility barriers, stem cell expansion, and prevention of complications and generation of graft-vs-tumor activity to eradicate residual disease. Stem Cell Transplantation for Hematologic and Other Disorders, Second Edition provides a glimpse into potential future applications of bone marrow derived stem cells in the field of cardiac repair. The updated chapters introduce the biologic underpinnings of hematopoietic cell transplantation, basic stem cell biology, immunobiology, and histocompatibility, with emphasis on indications and results of transplantation for specific diseases. Written by experts in the field, Stem Cell Transplantation for Hematologic Disorders, Second Edition provides seasoned professionals with a complete understanding of the current state of transplantation biology as well as a clear vision into the future.
Frau Bischoff, Frau Bischoff, wir haben ein Organ für Sie. In zehn Minuten werden Sie abgeholt zum Waschen und Rasieren. Sollen wir Ihre Mutter anrufen?´´ Die Worte rissen mich aus dem Schlaf. Die Stimme klang so weit weg, die Worte aber umso klarer. Was habe ich in diesem Moment gedacht? Ich weiß es nicht mehr. Ich weiß nur noch, was ich fühlte und das war Angst. Mein Schicksal hatte sich gegen das Sterben und für das Überleben entschieden. Was das bedeutete, wie schwer dieser Weg werden sollte, konnte ich zu diesem Zeitpunkt noch nicht erahnen.
Polymorphisms of genes implicated in the immune response after kidney transplantation are often linked with the recipients outcome. ICAM1, VCAM1, CTLA4 ang PTPN22 genes polymorphisms have been studied in regard to kidney transplantation. This book is a summary of the main findings of those studies and an attempt to describe the future perspectives of connection between genetics and transplantology.
This book presents international experimental and clinical experience on limb transplantation and other composite tissue allografts, representing the most complete and comprehensive review of this innovative and ground breaking procedure. This book is a milestone in medical literature and an asset for every scientific library.