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Frontiers of Cord Blood Science - Niranjan Bhat...
0,18 € *
zzgl. 3,99 € Versand

Cord blood is a significant source of hematopoietic stem and progenitor cells for the treatment of blood and genetic disorders. Cord blood is also an alternative to embryos as a source of tissue for regenerative medicine. Cells from cord blood have been shown to transdifferentiate into nonhematopoietic cells, including those of the brain, heart, liver, pancreas, bone, and cartilage, in tissue culture and in animal systems. Recently it has been demonstrated that both cardiac and glial cell differentiation of cord blood donor cells occurred in recipients of unrelated donor cord blood transplantation as part of a treatment regime for Krabbe disease and Sanfilippo syndrome. These observations raise the possibility that cord blood may serve as a source of cells to facilitate tissue repair and regeneration in the future. CD34 stem cell-rich umbilical cord whole blood transfusion has the potential to have an immediate benefit of better tissue oxygenation with an additional delayed benefit of possible engraftment of umbilical cord stem cells.

Anbieter: reBuy
Stand: 04.12.2020
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Hematopoietic Stem Cells
117,49 € *
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Hematopoietic Stem Cells ab 117.49 € als Taschenbuch: Animal Models and Human Transplantation. Softcover reprint of the original 1st ed. 1992. Aus dem Bereich: Bücher, Wissenschaft, Medizin,

Anbieter: hugendubel
Stand: 04.12.2020
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Hematopoietic Stem Cells
117,49 € *
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Hematopoietic Stem Cells ab 117.49 EURO Animal Models and Human Transplantation. Softcover reprint of the original 1st ed. 1992

Anbieter: ebook.de
Stand: 04.12.2020
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Retinal Degenerative Diseases
232,22 € *
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Contains the proceedings of the XVI International Symposium on Retinal Degeneration (RD2014), to be held July 13-18, 2014 at the Asilomar Conference Center in Pacific Grove, California. A majority of those who will speak and present posters at the meeting will contribute to this volume. The Symposium addresses the blinding diseases of inherited retinal degenerations, which have no effective treatments and age-related macular degeneration, which has no cures, despite the fact that it is an epidemic among the elderly, with 1 in 3-4 affected by the age of 75. The RD2014 Symposium will focus on the exciting new developments aimed at understanding these diseases and providing therapies for them.The volume will present representative state-of-the-art research in almost all areas of retinal degenerations, ranging from cytopathologic, physiologic, diagnostic and clinical aspects, animal models, mechanisms of cell death, molecular genetics, and developing potential therapeutic measures such as gene therapy and neuroprotective agents for potential pharmaceutical therapy, and several sight restoration approaches, including optogenetics. While advances in these areas of retinal degenerations will be included, several new topics either were in their infancy or did not exist at the time of the last RD Symposium, RD2012. These include many new developments in sight restoration using optogenetics, retinal or RPE cell transplantation, stem cell approaches and visual prosthetic devices. In addition, major advances will be presented in other basic mechanisms in age-related macular degeneration, several new aspects of gene and antioxidant therapy and revolutionary new imaging and functional testing that will have a huge impact on the diagnosis and following the course of retinal degenerations, as well as to provide new quantitative endpoints for clinical trials. The retina is an approachable part of the central nervous system (CNS), and there is a major interest in neuroprotective and gene therapy for CNS diseases and neurodegenerations, in general. It should be noted that with successful and exciting initial clinical trials in neuroprotective and gene therapy, including the restoration of sight in blind children, the retinal degeneration therapies are leading the way towards new therapeutic measures for neurodegenerations of the CNS. Many of the successes recently reported in these areas of retinal degeneration sprang from collaborations established at previous RD Symposia, and many of those will be reported at the RD2014 meeting and included.

Anbieter: Dodax
Stand: 04.12.2020
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Bone marrow stem cell therapy for stroke
162,70 € *
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This book covers recent advances in all aspects of bone marrow-derived stem cells (BMSCs) for stroke treatment, while also providing comprehensive information on human clinical trials and animal models of stroke. In addition, it reviews the optimal conditions of transplantation for stroke therapy and potential mechanisms underlying transplanted cell-mediated functional recovery after stroke. As the first book to focus on BMSC therapy for stroke, it also discusses in depth the unique challenges of BMSCs-based therapy in this context.

Anbieter: Dodax
Stand: 04.12.2020
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Cellular Therapy for Stroke and CNS Injuries
171,19 € *
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Cellular therapy for stroke and neural trauma has gained worldwide attention during the last decade and has shown some promising results. Various cells, including neural stem cells, bone marrow stem cells, endothelial progenitor cells, and many others have had protective or regenerative effects in animal models. The proposed book will address recent research on all relevant cell types.  In addition, it will provide information on cell isolation and culture skills, transplantation methods, and neurological functional evaluations. This is the first book to focus on cellular therapy for stroke and other CNS injuries.

Anbieter: Dodax
Stand: 04.12.2020
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Frontiers of Cord Blood Science
181,89 € *
ggf. zzgl. Versand

Cord blood is a significant source of hematopoietic stem and progenitor cells for the treatment of blood and genetic disorders. Cord blood is also an alternative to embryos as a source of tissue for regenerative medicine. Cells from cord blood have been shown to transdifferentiate into nonhematopoietic cells, including those of the brain, heart, liver, pancreas, bone, and cartilage, in tissue culture and in animal systems. Recently it has been demonstrated that both cardiac and glial cell differentiation of cord blood donor cells occurred in recipients of unrelated donor cord blood transplantation as part of a treatment regime for Krabbe disease and Sanfilippo syndrome. These observations raise the possibility that cord blood may serve as a source of cells to facilitate tissue repair and regeneration in the future. CD34 stem cell-rich umbilical cord whole blood transfusion has the potential to have an immediate benefit of better tissue oxygenation with an additional delayed benefit of possible engraftment of umbilical cord stem cells.

Anbieter: Dodax
Stand: 04.12.2020
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Hepatocytes
235,39 € *
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Hepatocytes account for approximately 80% of the liver mass and play a significant role in various aspects of liver physiopathology, exhibiting unrivaled complexity and diversity of functions. In Hepatocytes: Methods and Protocols , expert researchers provide the reader with methods, technical protocols, and review chapters focusing on selected areas of hepatocyte biology including isolation, culture, differentiation and stem cells, and hepatocyte use in clinical, basic, and applied research. With a specific emphasis on human hepatocytes, the volume presents chapters covering subjects including hepatocyte culture models, cryopreservation methods, differentiation assessment, liver ontogenesis, production of hepatocytes from stem cells, drug/xenobiotic metabolism, toxicity and transport, bile acid and blood coagulation factor production, infection by HBV and HCV, humanized animals, biortificial liver devices, hepatocyte transplantation. As a volume in the highly successful Methods in Molecular Biology (TM) series, protocol chapters include brief introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls.Comprehensive and cutting-edge, Hepatocytes: Methods and Protocols will be useful to all those who are currently using or planning to use human, or animal, hepatocytes to investigate any aspect of liver physiopathology or who are interested in liver development or liver stem cells and liver biotherapy.

Anbieter: Dodax
Stand: 04.12.2020
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Biological Approaches to Spinal Disc Repair and...
139,99 € *
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Although there have been significant advancements in minimally invasive spinal surgery techniques in the last few decades, optimal outcomes for chronic low back pain remain elusive. A number of promising clinical trials have been conducted using tissue engineering and biological interventions for disc degeneration. Written by renowned innovators, this is the first book that covers implementation of these groundbreaking approaches for disc disease.The text begins with key fundamentals including anatomy and physiology, pathophysiology, imaging and biomechanics to delineate healthy versus diseased spine. Subsequent sections discuss treatment strategies, research findings, and future developments. Throughout each chapter, renowned spine surgeons and scientists share clinical pearls gleaned from hands-on experience.Key HighlightsThe current state of the art in biological and tissue engineering procedures for spinal disordersTreatment methodologies including nucleus replacement and repair, annulus fibrosus repair, total disc transplantation, and mechanical total disc replacementInnovative treatment strategies for disc regeneration, such as genes and proteinsGrowth factors including platelet-rich plasma (PRP), which has shown promise for the stimulation and acceleration of bone and soft tissue healingCell-based therapy for spinal disc regeneration and repair including the use of stem cells and chondrocytesIn-depth discussion of research including animal versus human model, in-vitro, and a summary of biologic clinical trialsThis is a must-have resource for trainee and practicing orthopaedic surgeons and neurosurgeons who treat patients for spine-related conditions. It is essential reading for all clinicians who have an interest in cutting-edge tissue engineering and biological treatment interventions.

Anbieter: Dodax
Stand: 04.12.2020
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